
SkinCeuticals Advanced RGN-6 Reviews
4.7 ★ · 62 verified customer reviews · from $195.00
62 reviews
Customer reviews
Astrid M.
★★★★★
Skin felt smoother and healed after microneedling in 2 days! Usually takes 3-4 days for skin to return to normal. Really impressed at the suppleness in my skin. It's worth every penny to just have on hand - I'm glad I can use for daily use too so even better! I use a ton of skinceuticals and it's my favorite medical grade skincare.
Brian T.
★★★★★
My skin feels so soft after using this cream. I have not seen reduction of brown spots yet but I expect it will take a bit of time and use.
Jen R.
★★★★★
This helps right after injections or anytime you want your skin to look amazing!
Monica H.
★★★★★
I think this has helped my skin texture. It feels so much softer and smoother.
Jacqueline D.
★★★★★
I am in love with this product it is lightweight but hydrating enough..it is worth the price!!
Michelle
★★★★★
Skinceuticals Regen-6. I can say however that my face has never felt so soft and smooth. I have never had problem skin so I didnt realize how much softer it could get. It does minimize the look of a few fine lines I have on my forehead and absorbs beautifully into skin. I did a TCA peel at home and applied this afterwards. My skin feels perfectly hydrated using this as well and I also use Skinceuticals face wash which makes a dramatic difference as well. Seems to be packed with great ingredients...
Sara
★★★★★
Nice but could be better. I love the pump packaging and texture of this product. Nice list of ingredients which I was excited about. It doesnt take a lot to cover my face so the bottle should last longer than my SC jar moisturizers. This does feel nice on my skin but, even in Summer, this isnt hydrating enough for my dry mature skin. I am using it as a final serum/pre-moisturizer. This has many excellent reviews and I agree that this is an excellent product for many people. Im just not sure it i...
Aubrey
★★★★★
Holy Grail Anti-Aging Product. I was going to wait to review this product as Ive only used it for one week, however, it is such a fantastic product I decided to go ahead and review it. In just one week it has already given my skin a beautiful glow and increased the smoothness. The fine lines have disappeared and the deeper forehead lines look softer. I am 59 and my skin tends to dryness, so I put a either AGE Age Interrupter or Triple Lipid Restore on top of this. The two together keep my skin f...
Heather
★★★★★
Wonderful! Skinceuticals Advanced RGN-6 Regenerative Cream. I bought SkinCeuticals Advanced RGN-6 Regenerative Cream after reading a very favorable review that said it is amazing. Well, its true. I love it! First, it is a light feeling cream and provides full coverage with just 2 pumps. It also has a very slight pleasant fragrance. After just 2 days my skin looked smoother and felt very moisturized. Now after several weeks my skin looks more radiant and fine lines are less noticeable. I am a ski...
Tillie
★★★★★
Surpised at the Results. Ive only been using this for only 2 weeks, but I am amazed at how much nicer my skin feels and looks. I have been using SkinCeuticals products for a few years, and I went ahead and took the leap (as it is pricey) and tried this. My nose to mouth lines and my saggy jowls have improved. The texture of my skin is not as rough, and my face feels more moisturized. I basically switched my Age Interrupter Advanced moisturizer for this product. Im so glad I decided to try this a...
Monica
★★★★★
Excellent!!. SkinCeuticals RGN-6 Regenerative Cream lives up to everything the description says it should do! Quicker results than most products. My skin was softer and dewier within 3 days. It is the most advanced product to date; worth the money though it is a pricey splurge. I offer a warning. The pump is quite fragile and the lid comes off easily. When picking it up make sure to hold it by the bottle, not the lid. If it drops the pump will no longer work.
Nora
★★★★★
Too new to know. It is too early to tell whether this is making any substantial changes. But, I will say that while it goes on nicely and delivers out of the container nicely, it seems to leave your skin kind of sticky feeling. It needs time to soak in and then absolutely requires a good moisturizer on top. So, after one or two serums on different problems, this formula, and the moisturizer feels like a lot especially at bedtime.
Paige
★★★★★
Amazing!. Ive only started using this recently but its definitely becoming my favorite moisturizer ! The texture is amazing and I can literally see immediate results. There is no greasy residue or pilling. It works well under makeup. I like that its in an air tight pump dispenser. I feel like this will be in competition with Triple Lipid Restore 2:4:2 for the most fabulous product ever from the Skinceuticals brand
Abigail
★★★★★
Nice Product. For some background, I am a pale 34-year-old woman with sensitive skin that has some redness and light wrinkles. I tried this product without any Botox or other cosmetic procedures. That said, I enjoy this product. It has an amazing texture, and it does not irritate my skin. While I dont think my skin is the target for dramatic changes, I did notice that the one line I tend to get across my forehead appears much lighter. I also achieve the 'glass skin' effect with it. It may be too...
Maly
★★★★★
Wonderful. Ive been using skinceuticals vitamin C for years and it works great, adding RGN-6 to my skin routine has done wonders for me. Im in my late 40s and have no wrinkles, so I cant attest as to how well this works on wrinkles, but my face and complexion look brighter, I am glowing! My skin texture is smoother, pores are less visible and I actually have glass looking skin. I also apply RGN-6 on my neck and it looks firmer. Its only been a couple of days, but I already see results. I wash my...
Ajasmin
★★★★★
Ineffective assistance of cream. I was so looking forward to trying this because I needed a little more help with my aging skin. I am 46, and having ridden horses for years, my face has been subjected to all of the elements. I have used Skin Ceuticals for over 10 years, and I have never been disappointed, that is until I tried this product. I used it as directed, and the texture of it was nice. There was not any change to my skin that was positive. Instead it became ruddy, and I broke out contin...
Michelle
★★★★★
Great product. This is a great overall product. I used it after minimally invasive laser resurfacing and it seemed to heal a lot quicker with less peeling. I also notice an overall better glow and plumpness that I didnt have before. I get laser often so it was definitely different than getting laser without using this product and I have had no bad skin reactions and I actually notice a lightening of my dark spots during the summer months where there is sun exposure soo thats pretty impressive!!!
Brooke
★★★★★
Works incredibly like no other!. Yes! This is truly the most amazing and I mean seriously truly the most amazing product in town that absolutely works 100 percent guaranteed! I love this product and no doubt will order another one right away. Lets say you slept on your face wrong and now you have this deep line embedded into your face if you apply a small amount to your face the line disappears pretty quickly in a few minutes to half hour depending how deep that line was. That line was a frown l...
Sara
★★★★★
Quick Results!. SkinCeuticals has done it again! This moisturizer is a game changer for sure! After using a few times morning and night, I have noticed fast results in old blemish marks disappearing. I love the texture of the moisturizer. Feels so nice on, does not pill and no scent. A little goes a long way, which is awesome. Highly recommend!
Abigail
★★★★★
Really cutting edge product. Absolutely love this product! I have only been using for a couple of weeks but can honestly say I can see a difference in my skin. Its firming and sinks in easily and feels and smells great. Nit greasy, smooth. People have recently been spontaneously commenting on how good my skin looks... could be because of this!
Abigail
★★★★★
LOVE! LOVE! LOVE!. My skin hated me last week and was extremely angry. So, this product could not have come at a better time! The product feels like a blend of lotion and gel. It goes on smoothly, is lightweight, and has a slight cooling effect for a refreshing feel. It provides a glass skin look without being overdone. Im excited to see the long-term changes. However, after 2 days, I am very impressed!
Addison
★★★★★
Over delivers, will buy for life!. This product is amazing. I am 42 and still do not need a moisturizer for my face and so do not often buy them. However, this product has made a marked difference in my dark spots and it addresses acne. I have spent money on acne products. This works, by the next morning most of my face acne is resolved and after dedicated use stubborn stress acne on my neck resolved. I have had a dark spot under my eye for the past three years, and only after two bottles of this ...
Darina
★★★★★
Product, but not the packaging. Im 29, struggling from redness and on my second bottle. Unfortunately, the bottle fell right after puchasing on the pump and no product is being dispensed ever since. The support sent me an AI-generated response I assume because they suggested to squeeze the bottom (of a glass bottle??). This is super upsetting. I have great product that i can not retrieve from the packaging.
Peachie
★★★★★
convenient. I have been using this for a few weeks and the jury is still out. It does absorb easily but doesnt feel as moisturizing as AGE Interrupter or the Lipid Cream. Will be a while before I am sure which is best for me. It does have a very nice fragrance.
Tillie
★★★★★
SkinCeuticals Advanced RGN. This cream has such a nice texture. It absorbs very quickly and does not leave your skin feeling greasy. Ive only used it for a short while, so I have not noticed any significant skin improvement. However, SkinCeuticals has such nice, quality products, Im sure it will work as promised given a little time.
Heather
★★★★★
Amazing Fast Results. I have been using this duo now for about three weeks and I am very impressed with the results. I suddenly one day woke up and realized I had wrinkles around my mouth and red capillaries throughout my cheeks. Since using this, the wrinkles around my mouth are softening, and my skin is much clearer and I cannot see Those little capillaries. I cant wait to see what my skin looks like at six weeks. Do not hesitate to purchase this duo.
Linda
★★★★★
Still deciding. I decided to try this cream on my skin during the hot sunny summer. Even with spf I was finding my cheek area slightly pink. I wanted something that would calm down this area of my face. It seems to be working. Unfortunately I knocked the bottom the vanity and that has messed up the pump. I have managed to pull the inner part out and squeeze it each time I apply. I can see quite a lot of cream still in it but eventually will have to cut it with scissors. The plus is the bottle is...
Brianna
★★★★★
A change Maker. I just purchased this product, but noticed a difference in the texture, tone, and integrity of my skin within days of using it. I was using it twice a day, but have started to use it only at night to make it last longer. Using it once a day has generated consistent results. I would strongly recommend this product for others.
Abux
★★★★★
Great addition to the suite of skin products. So far I really like the way this addition my daily program. I went for Botox this week and my derm said my skin looked so great and what had I be doing? Advanced RGN my only change so I believe its working. I have very reactive skin to new products particularly on my neck and I have had no issues.
Herrin
★★★★★
My new Skinceuticals favorite!. I didnt think I would ever find a moisturizer I loved more than triple lipid. I was wrong. This product is light, yet very moisturizing, easy to apply and, in short, is perfect for summer when my beloved triple lipid can feel like 'too much' BRAVO Skinceuticals! this is a winner.
Wilmarie
★★★★★
Advance RGN-6 Regenerative cream. Ive been using Advance RGN-6 for about a month and a half. My skin looks more moisturized, clearer (the redness has decreased), and my expression lines have softened and my skin is smoother. I recommend it 100%.
Sands
★★★★★
Wonderful. I love this product. I use it every night and wake up with soft radiant skin. It is the perfect addition right when I needed one. My face was looking rather dull and dry and this just corrected in all the right needs. I have very fair skin and in my late 50s while I am outside all the time. I have been using Skin Ceuticals products for well over 20 years. I encourage everyone to try it.
Sara
★★★★★
Good as a moisturizer. I use it as a moisturizer at night, not as a regenerative treatment after a procedure . I think it is a good anti aging cream but I noticed it caused some milia on my cheeks. Other than that I like the moisturizing and brightening I see when I wake up in the morning.
Ire
★★★★★
Excellent product. I usually alternate SkinCeuticals C E Ferulic and SkinCeuticals P-TIOX in the morning and I started using SKINCEUTICALS ADVANCED RGN-6 REGENERATIVE CREAM after applying those everyday. I have started seeing results after 2 weeks. My under eye and. forehead wrinkles are less visible.
Daria
★★★★★
Good enough. The texture is really nice - not too heavy, not greasy - and it sinks into my skin super easily. My skins been feeling smoother and just healthier . If youre thinking about trying it, Id say go for it. Low-key gem.
Julia
★★★★★
Awesome product. Before using this product my skin looked dull and dry and my pores where huge, after using this for a couple of weeks my skin feels tight and it looks a lot more hydrated and the size of my pores has definitely reduced, really loved this product.
Linda
★★★★★
Another winner. Started using this after a laser procedure. I have had laser procedures before without using rgn-6. I believe rgn -6 improved my healing time. I am still using it. Nice creamy consistency, no scent, spreads nicely.
Sara
★★★★★
New favorite SkinCeuticals product...... that I cant live without! I thought Id give it a try as I am loyal to SkinCeuticals. Ive almost finished my first bottle (I just ordered a 2nd) and I believe it transformed my skin! It is pricey and since I dont do lasers or any facial treatments, I briefly hesitated on buying this 2nd bottle but so glad I did. In my opinion, its magical!
Heather
★★★★★
Great product!. Before using this product, my skin looked dull and dry and my pores where huge. After using this for a couple of weeks, my skin feels tighter, more hydrated & my pores look smaller. Highly recommend!
Broncobarb
★★★★★
RGN-6 Regenerative Cream. I have purchased this twice and have been using it after C02 Laser. It did not irritate, and I believe it helped improve the red skin. It is difficult to tell when it is going to run out because you cannot see thru the bottle and it heavy.
Josephine
★★★★★
SkinCeuticals RGN-6. Product is fabulous. My skin is hydrated and much smoother. The fine lines I had are no longer noticeable. Overall, face redness is diminished and skin texture is much improved. Definitely recommend product.
Stephanie
★★★★★
I can see a difference. I am in my mid-40s and aging is showing on my face. While this isnt a huge difference, it is certainly more of a difference I have seen than other products. The only reason for 4 stars is its astronomical price. It just seems wrong. But I will do anything to protect my youth, so I may buy it again!
Sara
★★★★★
Skin care. So far very happy with this new product. I use this morning and evening, the week before an in office procedure and a few days after. It seems to help my skin heal. All I can say is my skin looks great. Getting lots of compliments! Expensive but you only use a little each time. Totally try it!
Fran
★★★★★
Price aside, this is a winner. Other than its price ( high) Skinceuticals has come up with another good product. Even if you havent recently had face work this regeneration mix reduces wrinkles, has healing properties even for an old fave. Seems to combine some really fine attributes in one product.
Michelle
★★★★★
My favorite skincare product in 2025. I am very happy with this new skin regeneration cream - lightweight, moisturizing and has given me a more even completion. Used daily with SkinCeuticals serums as a base, my skin just seems more nourished.
Priz
★★★★★
Honestly. Have been using this new product for several weeks now and honestly its too soon to tell. I like the texture of the product and my skin feels soft but it needs more time to notice a difference.
Sara
★★★★★
Regenerative cream. Ive been using the Regenerative cream for a month and I notice softer skin and the fine lines have diminished. I really like how it feels on my skin.
Sara
★★★★★
Soothing. I used this after microneedling and it was very soothing and helped my skin recover faster. I have also used it other times when my skin felt irritated and got immediate relief. I will continue using as needed and plan to repurchase. Shared information with my esthetician.
Leah
★★★★★
Amazing!. This is an amazing product! Ever since I started using it, people are complimenting my skin. It both hydrates and smooths, feels amazing!
Buggy
★★★★★
Advanced RGN-6. I have not noticed a difference in my skin but hope that with continued use I will see improvement. I do like the way it goes on easy, and it feels nice on my face.
Teresa
★★★★★
Solid!. Product is easy to use. Ordering process was streamlined. Cost is better than other sites Took a bit longer than anticipated to receive product . Received cream, desired serum.
Emily
★★★★★
Love This New Regenerative Cream. I have been using the new regenerative cream by SkinCeutical for 2 weeks now, and my skin looks so much clearer. I use it morning and night. It is a little pricey, but it will last a long time....and I am worth it :)
Kendra
★★★★★
Better than competitor. I have another brands version of this. It works fine but has a silicone texture and does not blend well with other products. This stuff is creamy dreamy and easy to blend. Seems to work well too! Will reorder.
Stephanie
★★★★★
Amazing Product!. This cream is lightweight and a little goes a long way! I have noticed an improved texture of my skin, and less wrinkles after just 1 month!
Paige
★★★★★
All time favourite. Perfect for sensitive skin. Advanced age interrupt stoped working for me after the change in formula. This cream is doing wonder for my skin.,
Julia
★★★★★
Gold Star - Excellent. Product works great for improving fine lines and post blemish marks. Muktitasker absorbs well and skin looks good.
Fio
★★★★★
Incredibly effective. SkinCeuticals its a well-known brand because of these kinds of products, which do the work they promised. Its incredible for dark spots, post-acne marks, redness, etc. In one week you will see the results!
Claire
★★★★★
Not a miracle in a bottle. Expensive for what you get. I dont think it is 'advanced' and I am not seeing any results. For the price I want to see some changes. Will move onto a different product.
Max
★★★★★
Fantastic product! Highest accolades!. A little pricey, but definitely one of the finest skin conditioners I have ever used. My girlfriend and I both use this product daily, and we will reorder whe. We work through these two bottles.
Gabriella
★★★★★
Great evening product. I use this product in the evening and really like it. I use it after my Retinol. It makes a huge difference in lines on your face.
Stephanie M.
★★★★★
Great cream after laser treatments. Really like the Ellemes spa because they gave me a discount on a brand new product, and they did not have to.