SkinCeuticals Advanced RGN-6
SkinCeuticals Advanced RGN-6
SkinCeuticals Advanced RGN-6 alternate view
SkinCeuticals Advanced RGN-6 packaging view

SkinCeuticals Advanced RGN-6

$195.00
Shipping calculated at checkout.
#9 of 14 in Lighteners & Brighteners
Size: 1 fl oz (30 mL)

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Regenerative Cream
Renew And Restore
Suited for:
All skin types, post-treatment
Target concerns:
Redness, dark spots, wrinkles
Benefits:
Reduces redness, spots, wrinkles
When to use:
Morning and evening

DESCRIPTION
SkinCeuticals Advanced RGN-6 Regenerative Cream – A scientifically formulated renewal cream, inspired by laser regeneration research, that visibly reverses six signs of aging and uneven tone—reducing redness, dark spots, and wrinkles while improving smoothness and firmness in as little as one week.
  • Rejuvenates six dimensions of skin health: reduces redness, post-acne marks, dark spots, wrinkles while boosting smoothness and firmness
  • Supports barrier repair and renewal with 10 % Glyco‑Repair™ (a carob‑derived complex)
  • Soothes sensitivity and oxidative stress with 1 % eperuline and 0.2 % ectoin
  • Brightens and evens tone using 2 % niacinamide and 0.2 % bioceramide‑603
  • Firms and reinforces resilience through 3 % acetyl tetrapeptide‑9 peptide signal technology
Who benefits? Suitable for all skin types—including sensitive and post-procedure—ideal for those seeking a clinical-grade treatment to accelerate recovery, reduce redness and pigmentation, and strengthen firmness and texture.
  • Six Signs Addressed
  • Silky Comforting Cream
  • Niacinamide Core
  • Gentle For All
  • Post-Laser Partner
  • Serum Then Cream

PRODUCT DETAILS

How to use

Daily Application:
Cleanse thoroughly and apply SkinCeuticals Vitamin C antioxidant serum.
Dispense 1-2 pumps of Advanced RGN-6 into the palm.
Gently press onto the face, targeting the forehead, cheeks, and chin.
Follow with your favorite SkinCeuticals sunscreen in the morning.
Post-Laser Procedure Application:
Immediately apply Advanced RGN-6 after your laser treatment.
Continue applying twice daily to enhance recovery and rejuvenation.

Ingredients

Aqua / Water / Eau, Glycerin, Ethyl Oleate, Niacinamide, Squalane, C12-16 Alcohols, Glyceryl Stearate Citrate, Butyrospermum Parkii Butter / Shea Butter, Maltodextrin, Ammonium Polyacryloyldimethyl Taurate, Phenoxyethanol, Dimethicone, Palmitic Acid, Hydrogenated Lecithin, Cetyl Alcohol, Ceratonia Siliqua Seed Extract / Carob Seed Extract, Caprylyl Glycol, 2-Oleamido-1,3-Octadecanediol, Ectoin, Tocopherol, Eperua Falcata Bark Extract, Xanthan Gum, Ethylhexylglycerin, Phytic Acid, Adenosine, Sodium Hydroxide, Sodium Benzoate, Acetyl Tetrapeptide-9, Citric Acid
Best Sellers Rank: #107 of 227

Ranked by units sold, last 90 days

Ideal for these Concerns: Dark Spots & Hyperpigmentation, Dullness, Fine Lines & Wrinkles, Uneven Tone
SHIPPING & RETURNS

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For eligibility and return instructions, please see our returns policy.

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    SkinCeuticals Advanced RGN-6

    SkinCeuticals Advanced RGN-6

    How to use

    Daily Application:
    Cleanse thoroughly and apply SkinCeuticals Vitamin C antioxidant serum.
    Dispense 1-2 pumps of Advanced RGN-6 into the palm.
    Gently press onto the face, targeting the forehead, cheeks, and chin.
    Follow with your favorite SkinCeuticals sunscreen in the morning.
    Post-Laser Procedure Application:
    Immediately apply Advanced RGN-6 after your laser treatment.
    Continue applying twice daily to enhance recovery and rejuvenation.

    Ingredients

    Aqua / Water / Eau, Glycerin, Ethyl Oleate, Niacinamide, Squalane, C12-16 Alcohols, Glyceryl Stearate Citrate, Butyrospermum Parkii Butter / Shea Butter, Maltodextrin, Ammonium Polyacryloyldimethyl Taurate, Phenoxyethanol, Dimethicone, Palmitic Acid, Hydrogenated Lecithin, Cetyl Alcohol, Ceratonia Siliqua Seed Extract / Carob Seed Extract, Caprylyl Glycol, 2-Oleamido-1,3-Octadecanediol, Ectoin, Tocopherol, Eperua Falcata Bark Extract, Xanthan Gum, Ethylhexylglycerin, Phytic Acid, Adenosine, Sodium Hydroxide, Sodium Benzoate, Acetyl Tetrapeptide-9, Citric Acid
    The Skin Regenerator
    Why You'll Love It
    A regenerative daily cream that visibly improves six signs of aging and supports post-laser recovery.

    Scroll to see more product features

    • SkinCeuticals Advanced RGN-6

      Six Signs Addressed

      Diminishes redness, dark spots, acne marks, and wrinkles, with visible change in one week.
    • SkinCeuticals Advanced RGN-6

      Silky Comforting Cream

      A smooth cream with squalane and shea butter that cushions skin without any heaviness.
    • SkinCeuticals Advanced RGN-6 alternate view

      Niacinamide Core

      Niacinamide leads a considered formula that is free of parabens, fragrance, and alcohol.
    • SkinCeuticals Advanced RGN-6 packaging view

      Gentle For All

      Gentle enough for all skin types, including skin that is recovering from laser treatments.
    • SkinCeuticals Advanced RGN-6

      Post-Laser Partner

      Inspired by laser regeneration research, it helps minimize visible downtime after in-office treatments.
    • SkinCeuticals Advanced RGN-6

      Serum Then Cream

      Press one to two pumps onto skin after your vitamin C serum, morning and evening.
    Age-Defying Actives
    Key Ingredients

    Scroll to see more ingredients

    • Niacinamide
      Barrier Support
      Niacinamide helps refine the look of pores, support the moisture barrier, and promote a smoother, more balanced complexion.
    • Squalane
      Lightweight Moisture
      Squalane is a lightweight, skin-mimicking emollient that softens and conditions without feeling heavy or greasy on the skin.
    • Shea Butter
      Rich Nourishment
      Shea butter is a rich emollient that deeply nourishes and softens, helping to comfort dry and dehydrated-looking skin.

    Need to Know

    Frequently Asked Questions

    How do I fit RGN-6 into my daily routine?
    After cleansing, apply your SkinCeuticals vitamin C serum first, then press one to two pumps of RGN-6 onto the forehead, cheeks, and chin. In the morning, always finish with sunscreen.
    Can I use it after a laser treatment?
    Yes, it's physician-tested to complement laser procedures. It can be applied immediately after treatment and continued twice daily to help support recovery and reduce the look of downtime, following your provider's guidance.
    What signs of aging does it address?
    It's a regenerative cream formulated to visibly improve six concerns at once: redness, post-acne marks, dark spots, and wrinkles, along with smoothness and firmness, with some results reported in as little as one week.
    Is it gentle enough for sensitive skin?
    It's suitable for all skin types, including sensitive and post-procedure skin, and it's free of parabens, fragrance, and alcohol. Its soothing ingredients like ectoin help keep it comfortable.
    Does it replace my vitamin C or sunscreen?
    No, it's meant to work alongside them. It layers over your antioxidant serum and under your SPF, so your full regimen of vitamin C in the morning and sunscreen still applies.

    Product Comparison

    Find your best match

    Scroll horizontally to compare products.

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    Suited for All skin types, post-treatment Oily, acne-prone skin All skin types Mature, aging skin
    Target concerns Redness, dark spots, wrinkles Breakouts, congestion, uneven texture Fine lines, uneven tone, rough texture Sagging, deep wrinkles, dullness
    Key ingredients Niacinamide, Peptides, Ectoin: Post-Treatment Renewal. AlphaRet, Salicylic, Niacinamide: Clears, Smooths. AlphaRet, Vit C, Peptides: Overnight Renewal. Pro-Xylane, Ectoin: Tightens, Firms Skin.
    When to use Morning and evening Nightly after cleansing Nightly, thin layer Once or twice daily
    Key benefits Reduces redness, spots, wrinkles Clears breakouts, refines, calms Smooths lines, evens tone, hydrates Tightens, smooths wrinkles, hydrates
    Price
    $195.00
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    Ratings
    4.7
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    Availability In stock In stock In stock In stock

    Reviews

    4.7

    Based on 63 reviews

    Showing 1–5 of 63 reviews

    Emily H.

    Most amazing face product that exists and I’ve tried so many, this brand is the best!

    Alexandra S.

    A favorite product of mine! Received quickly as usual! Thank you!

    Astrid M.

    Skin felt smoother and healed after microneedling in 2 days! Usually takes 3-4 days for skin to return to normal. Really impressed at the suppleness in my skin. It's worth every penny to just have on hand - I'm glad I can use for daily use too so even better! I use a ton of skinceuticals and it's my favorite medical grade skincare.

    Brian T.

    My skin feels so soft after using this cream. I have not seen reduction of brown spots yet but I expect it will take a bit of time and use.

    Jen R.

    This helps right after injections or anytime you want your skin to look amazing!

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