Jonathan S.
This is a great product. It absorbs well and has greatly improved my skin.
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Most antioxidant serums rely on a single ingredient — usually vitamin C — to neutralize free radicals. The problem is that environmental damage comes from multiple sources (UV radiation, pollution particulates, blue light from screens, infrared heat) and each generates different types of oxidative stress. SkinBetter Science Alto Defense Serum addresses this with a blend of 19 distinct antioxidants, each targeting a specific pathway of environmental damage.
The formulation includes multiple forms of vitamin C for surface and deeper-layer protection, vitamin E for lipid barrier defense, and a spectrum of polyphenol antioxidants derived from botanical sources. These include extracts that target reactive oxygen species, reactive nitrogen species, and metal-catalyzed oxidation — the three primary categories of free radical damage responsible for premature skin aging. The multi-pathway approach means the serum continues working even when individual antioxidants are depleted, providing more consistent daily protection than single-antioxidant formulas.
Apply 1-2 pumps to clean, dry skin every morning. Gently press into face, neck, and décolletage. Follow with moisturizer and broad-spectrum SPF. Alto Defense is lightweight and layers easily under sunscreen and makeup. It can be used alongside retinoids in an evening routine, though its primary function is daytime environmental defense.
Patients typically report visibly brighter, more even-toned skin within 4-6 weeks of daily use. Because the serum works primarily as a preventive measure — defending against ongoing environmental damage rather than reversing existing damage — its benefits compound over months of consistent application. The texture is a lightweight, fast-absorbing fluid with no residue.
All skin types seeking comprehensive daily environmental protection. Particularly well-suited for patients who spend time outdoors, live in urban areas with higher pollution exposure, or use screens for extended periods. Works for sensitive skin types who may not tolerate high-concentration pure vitamin C formulas.
Professional-Only Note: SkinBetter Science products are available exclusively through authorized medical providers. They are not sold on Amazon, at Sephora, or through any retail channel. This ensures product authenticity and proper guidance from your provider.
Recommended by ELLEMES providers as a daily environmental shield. Pairs particularly well with in-office treatments — use it to protect your investment in professional skincare procedures.
For delivery information and shipping options, please see our shipping policy.
For eligibility and return instructions, please see our returns policy.
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SkinBetter Science Alto Defense Serum
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Showing 1–5 of 64 reviews
Jonathan S.
This is a great product. It absorbs well and has greatly improved my skin.
Kimberly C.
Dulled my skin and caused breakouts in the first few weeks of use. I have sensitive skin and dry skin, and usually my issue with skin care is irritation but never dullness and breakouts. I stuck with it and still didnt see any improvement after over a month of use. For this price, I need to be wowed. I will not reorder.
Jessie N.
Ive been using Alto Defense Serum on a daily basis for years. It is the perfect balm to protect my skin, regardless of season.
Rose B.
Love ! Cannot go a day without it, I notice a huge difference with using this product vs without
Isabelle F.
Already notice a difference in a month of using this consistently!