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SkinMedica Age Defense Retinol Complex 0.5

Regular price $80.00
Shipping calculated at checkout.
Size: 1 fl oz (30 mL)
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Nightly retinol that smooths lines and texture.
Product Info

SkinMedica Age Defense Retinol Complex 0.5 – A nightly retinol treatment that pairs 0.5% retinol with the antioxidant PhytoShield™ Complex, niacinamide, and a peptide-and-ceramide base to renew skin and soften the look of fine lines, wrinkles, and uneven texture.

Smooths the appearance of fine lines and coarse wrinkles
Enhances skin tone, texture, and resiliency
PhytoShield™ Complex encapsulates retinol for targeted delivery
Helps minimize the irritation often associated with retinol
Formulated for skin already conditioned to retinol

Who benefits? Ideal for all skin types pre-conditioned with Retinol Complex 0.25 or another retinoid, perfect for anyone ready to step up their nightly renewal for smoother, more youthful-looking skin.

How to Use

Apply a single pump in the evening after cleansing and toning, before your moisturizer. If you are new to retinol, begin twice a week, gradually increasing to every other night and then nightly as tolerated. Apply to the entire face, avoiding the eyes. Use a broad-spectrum SPF 30 or higher daily while using this product. Do not use if pregnant, lactating, or planning to become pregnant.

Shipping

When will my order be shipped?

We aim to ship all products the same or next business day (Monday - Friday, excluding holidays) if in stock. If a delay occurs due to manufacturer backorders, we will notify you via email.

When will my order arrive?

Most orders are delivered within 2-3 business days, with over 99% arriving within 7 business days. Delivery times depend on the distance from our Atlanta, GA, location and the carrier.

How do I track my order?

Once your order ships, you will receive an email with a tracking number to monitor delivery progress.

What if my tracking number says "delivered" but I can't find my package?

Check your front/back porches, side doors, garage areas, and with neighbors. If the package is still missing after 2 business days, contact us for assistance.

Help Center?
Contact us and one of our skin experts will be happy to help!

Retinol Complex

Age-Defying Nightly Renewal
Suited for:

All skin types, retinol-conditioned

Target concerns:

Fine lines, wrinkles, uneven texture

Benefits:

Smooths, renews, refines

When to use:

Evening

The Nightly Renewer

Why You'll Love It

A 0.5% retinol night treatment that renews skin and softens the look of lines and wrinkles.

SkinMedica Age Defense Retinol Complex 0.5

Smooths Lines & Wrinkles

Renews skin overnight to soften the look of fine lines and coarse wrinkles.

PhytoShield™ Complex

An antioxidant complex encapsulates retinol for targeted delivery and helps minimize irritation.

Refines Texture

Encourages surface renewal so skin looks smoother and more even over time.

Gentler On Skin

The PhytoShield™ Complex helps make retinol more comfortable than many traditional formulas.

Age-Defying Renewal

Key Ingredients

Skin Renewal
Retinol

Skin Renewal

Retinol encourages surface cell turnover to soften the look of fine lines and wrinkles, refine texture, and reveal fresher, more radiant-looking skin.

PhytoShield™ Complex
Antioxidant Shield

PhytoShield™ Complex

The PhytoShield™ Complex is an antioxidant blend that encapsulates retinol for targeted delivery while helping to minimize the irritation often linked to retinol use.

Niacinamide
Tone & Texture

Niacinamide

Niacinamide helps improve the look of uneven tone and texture while supporting a smoother, more radiant-looking complexion.

Need to Know

Frequently Asked Questions

Everything you need to know before choosing, using, and caring for your skin with Purity products.

Explore Help Center
What makes Retinol Complex 0.5 different?

It delivers 0.5% retinol encapsulated in SkinMedica's antioxidant PhytoShield™ Complex, which supports targeted delivery and helps minimize the irritation often associated with retinol.

Who should use the 0.5 strength?

It's formulated for skin already conditioned to retinol, whether you've used Retinol Complex 0.25 or another retinoid. If you're brand new to retinol, start with the 0.25 first.

How and when do I apply it?

Apply a single pump in the evening after cleansing and toning, before your moisturizer. Begin a few nights a week and build up to nightly as tolerated.

Can I use it during pregnancy or while nursing?

Retinol is generally advised against during pregnancy and breastfeeding. Pause it during that time and ask your doctor which ingredients are appropriate for you.

Do I still need sunscreen?

Yes, always. Retinol increases sun sensitivity, so wear a broad-spectrum SPF 30 or higher every morning to protect your skin and preserve results.

What should I expect at first?

Mild redness, peeling, or dryness can occur as your skin adjusts. Keep skin moisturized and stay consistent; smoother texture and a more even tone typically build over several weeks.

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Not sure if this product is right for you?

Schedule a virtual consultation with Expert Esthetician Lauren Siso today!

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Refines Texture
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PhytoShield™ Complex
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PhytoShield™ Complex
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PhytoShield™ Complex
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PhytoShield™ Complex
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Smooths Lines & Wrinkles
PhytoShield™ Complex
Refines Texture
Smooths Lines & Wrinkles
PhytoShield™ Complex
Refines Texture
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PhytoShield™ Complex
Refines Texture