White SkinMedica TNS Ceramide Treatment Cream tube against a light blue background.
SkinMedica TNS Ceramide Treatment Cream tube with a white cream swatch beside it.
Old silver and new white SkinMedica TNS Ceramide Treatment Cream tubes shown side by side.
SkinMedica TNS Ceramide Treatment Cream tube and cream swatch beside a product overview.
Three smiling models in a SkinMedica TNS Ceramide Treatment Cream graphic.

SkinMedica TNS® Ceramide Treatment Cream

$72.00
Shipping calculated at checkout.
Size: 2 fl oz

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Barrier Moisturizer
Restore And Comfort
Suited for:
Dry, sensitive, post-procedure skin
Target concerns:
Dryness, compromised barrier, rough texture
Benefits:
Deeply hydrates, restores barrier
When to use:
Twice daily or as needed

DESCRIPTION

SkinMedica TNS® Ceramide Treatment Cream – A rich, restorative treatment moisturizer combining TNS® growth factor technology, peptides, and patented Ceramide technology to deeply hydrate, support the skin barrier, and comfort dry or compromised skin.

Hydrates and restores skin’s moisture balance
Supports the skin’s natural moisture barrier
Features TNS® growth factor technology for skin support
Combines peptides and ceramide technology to improve texture
Rich, comforting cream ideal after treatments or for dryness

Who benefits? Ideal for all skin types, especially dry, sensitive, mature, compromised, or post-procedure skin, perfect for those needing a richer moisturizer that supports barrier repair, hydration, and smoother, healthier-looking skin.

  • Deep Moisture Repair
  • Rich, Comforting Cream
  • TNS Plus Ceramides
  • Post-Procedure Comfort
  • Smoother, Calmer Skin
  • Final Routine Step

PRODUCT DETAILS

How to use

Apply twice daily or as often as needed after cleansing, toning, and using treatment products. Apply a small amount to the entire face, neck, and décolleté, then gently massage into the skin. Avoid getting in eyes; if contact occurs, rinse eyes thoroughly with water.

Ingredients

Aqua/Water/Eau, Cetyl Ethylhexanoate, Cetearyl Alcohol, Hydroxypropyl Bispalmitamide MEA, Human Fibroblast Conditioned Media, Dimethicone, Olea Europaea (Olive) Fruit Oil, Glycine Soja (Soybean) Oil, Glycerin, Cetearyl Glucoside, Squalane, Glyceryl Stearate, PEG-100 Stearate, Palmitoyl Tripeptide-1, Palmitoyl Tetrapeptide-7, Tetrahexyldecyl Ascorbate, Avena Sativa (Oat) Kernel Extract, Glycine Soja (Soybean) Sterols, Retinyl Palmitate, Tocopheryl Acetate, Sodium Carboxymethyl Beta-Glucan, Allantoin, Bisabolol, Panthenol, Sodium Hyaluronate, Xanthan Gum, Polysorbate 20, Isoceteth-20, Butylene Glycol, Ethoxydiglycol, Carbomer, Disodium EDTA, Ethylhexylglycerin, Phenoxyethanol, Caprylyl Glycol, Caprylhydroxamic Acid, Potassium Sorbate
Best Sellers Rank: #210 of 227

Ranked by units sold, last 90 days

Ideal for these Concerns: Damaged / Post-Procedure Barrier, Dryness & Dehydration, Uneven Texture
SHIPPING & RETURNS

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For eligibility and return instructions, please see our returns policy.

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    SkinMedica TNS® Ceramide Treatment Cream

    White SkinMedica TNS Ceramide Treatment Cream tube against a light blue background.

    How to use

    Apply twice daily or as often as needed after cleansing, toning, and using treatment products. Apply a small amount to the entire face, neck, and décolleté, then gently massage into the skin. Avoid getting in eyes; if contact occurs, rinse eyes thoroughly with water.

    Ingredients

    Aqua/Water/Eau, Cetyl Ethylhexanoate, Cetearyl Alcohol, Hydroxypropyl Bispalmitamide MEA, Human Fibroblast Conditioned Media, Dimethicone, Olea Europaea (Olive) Fruit Oil, Glycine Soja (Soybean) Oil, Glycerin, Cetearyl Glucoside, Squalane, Glyceryl Stearate, PEG-100 Stearate, Palmitoyl Tripeptide-1, Palmitoyl Tetrapeptide-7, Tetrahexyldecyl Ascorbate, Avena Sativa (Oat) Kernel Extract, Glycine Soja (Soybean) Sterols, Retinyl Palmitate, Tocopheryl Acetate, Sodium Carboxymethyl Beta-Glucan, Allantoin, Bisabolol, Panthenol, Sodium Hyaluronate, Xanthan Gum, Polysorbate 20, Isoceteth-20, Butylene Glycol, Ethoxydiglycol, Carbomer, Disodium EDTA, Ethylhexylglycerin, Phenoxyethanol, Caprylyl Glycol, Caprylhydroxamic Acid, Potassium Sorbate
    The Barrier Restorer
    Why You'll Love It
    A rich treatment moisturizer pairing growth factors with ceramides to hydrate and restore compromised skin.

    Scroll to see more product features

    • White SkinMedica TNS Ceramide Treatment Cream tube against a light blue background.

      Deep Moisture Repair

      Replenishes hydration and helps restore moisture balance for dry or compromised skin.
    • SkinMedica TNS Ceramide Treatment Cream tube with a white cream swatch beside it.

      Rich, Comforting Cream

      A plush, cushioning texture that soothes on contact without feeling greasy or heavy.
    • Old silver and new white SkinMedica TNS Ceramide Treatment Cream tubes shown side by side.

      TNS Plus Ceramides

      Growth factor technology, peptides, and patented ceramides support the skin's natural moisture barrier.
    • SkinMedica TNS Ceramide Treatment Cream tube and cream swatch beside a product overview.

      Post-Procedure Comfort

      A calming choice for sensitive, mature, or freshly treated skin that needs extra support.
    • Three smiling models in a SkinMedica TNS Ceramide Treatment Cream graphic.

      Smoother, Calmer Skin

      Improves texture and comfort so skin looks healthy, rested, and more resilient.
    • White SkinMedica TNS Ceramide Treatment Cream tube against a light blue background.

      Final Routine Step

      Apply after serums twice daily across the face, neck, and décolleté as needed.
    Hydration Heroes
    Key Ingredients

    Scroll to see more ingredients

    • Ceramide Complex
      Barrier Support
      This ceramide complex reinforces the skin barrier to seal in moisture and help keep the complexion supple and comfortable.
    • TNS
      Growth Factor Blend
      TNS is a proprietary growth-factor blend that supports skin rejuvenation to soften lines and improve tone and texture.
    • Peptide Complex
      Firming Support
      This peptide complex supports the look of firmness and helps soften the appearance of fine lines for smoother-looking skin.

    Need to Know

    Frequently Asked Questions

    What does this cream do?
    It hydrates and helps restore the skin's moisture balance while supporting a healthy barrier. TNS, peptides, and patented ceramide technology work together to improve texture and comfort dry or compromised skin.
    How do I use it?
    Apply it twice daily, or as needed, after cleansing, toning, and any treatment products. Massage a small amount into the face, neck, and decollete, keeping it away from the eyes.
    Where does it fit in my routine?
    It works as your moisturizer step, going on after serums and treatments to seal in hydration. In the morning, follow with sunscreen.
    Why are ceramides important?
    Ceramides are lipids that naturally help hold the skin barrier together and keep moisture in. Replenishing them supports skin that feels stronger, smoother, and more comfortable.
    Is it good for dry or post-procedure skin?
    Yes, it's especially suited to dry, sensitive, mature, post-procedure, or compromised skin thanks to its barrier-supporting formula. If you're recovering from a treatment, confirm timing with your provider.
    Can I use it around my eyes?
    You can apply it to the surrounding face and decollete, but avoid getting it directly in the eyes. For the delicate eye area itself, a dedicated eye product is a better fit.

    Product Comparison

    Find your best match

    Scroll horizontally to compare products.

    Product White SkinMedica TNS Ceramide Treatment Cream tube against a light blue background. SkinMedica TNS® Ceramide Treatment Cream This product SkinMedica HA5 Hydra Collagen Hydrator with Vegan Collagen SkinMedica HA5® Hydra Collagen Hydrator with Vegan Collagen Obagi Hydrate Luxe Obagi Hydrate Luxe Revision Skincare DEJ Face Cream Revision Skincare DEJ Face Cream
    Suited for Dry, sensitive, post-procedure skin All skin types Dry, normal, combination skin All skin types, even sensitive
    Target concerns Dryness, compromised barrier, rough texture Dehydration, fine lines, redness Dryness, fine lines, dullness Fine lines, dullness, uneven tone
    Key ingredients Ceramides, Peptides, Growth Factors: Barrier Moisture. HA, Vegan Collagen: Plumps, Hydrates. Peptides, Shea, Mango Butter: Rich Hydration. Vit C, Ceramides, HA: Brightens, Firms.
    When to use Twice daily or as needed Twice daily before moisturizer Evening, after treatments Morning and evening
    Key benefits Deeply hydrates, restores barrier Instantly hydrates, plumps, smooths Deeply hydrates, restores barrier Firms, brightens, smooths texture
    Price
    $72.00
    $192.00
    $85.00
    From $75.00
    Ratings
    5.0
    4.7
    5.0
    4.8
    Availability In stock In stock In stock In stock

    Reviews

    5.0

    Based on 6 reviews

    Showing 1–5 of 6 reviews

    Brian C.

    This is by far the best product Skin Medica offers that is instantly gratifying and hydrating. You will be surprised how quickly your skins absorbs it. It layers with the TNS serum perfectly.

    Danielle P.

    Best treatment cream ever! It’s light & not oily. If you have sensitive skin I highly recommend it!

    Meredith P.

    This is my second tube of TNS Ceramide Treatment. I love it. It feels so nice on my face and neck. It works will with all my other skin care and make up. It’s great post procedure too. I have very dry skin. I am mid 50’s with a lot of sun damage. It has provided subtle and consistent improvement in my skin’s texture. It’s gentel enough around my eyes and on my rosacea cheeks. I love it so much I cut the top off so I can get every last glob of it. I will continue to repurchase.

    John R.

    I purchased this for use after a procedure and it was hydrating, thick with a slightly "waxy" and creamy feel. This was not intrusive and felt great and contributed to a sensation that my skin was hydrated. I used this in conjunction with the post-procedure complex. I had no dryness and my skin felt great during the use of both over the recovery period. I will use this whenever my skin requires an extra soothing boost or moisture.

    Christina M.

    It’s a nice cream that works well before I use retin A

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