Hydrinity CÉLTHERA Advanced Overnight Repair Cream 50 mL pump bottle

Hydrinity CÉLTHERA Advanced Overnight Repair Cream 50 mL navy and rose-gold pump bottle on a dark gradient background

Hydrinity CÉLTHERA Advanced Overnight Repair Cream texture swatch showing the rich white cream

Model holding the Hydrinity CÉLTHERA Advanced Overnight Repair Cream pump bottle

Model with a swipe of Hydrinity CÉLTHERA Advanced Overnight Repair Cream on her cheek before massaging it in

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Hydrinity CÉLTHERA Advanced Overnight Repair Cream

Name: Hydrinity CÉLTHERA Advanced Overnight Repair Cream
Brand: Hydrinity
SKU: 850046513343
Price: 160.0 USD
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$160.00

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Size: 50 mL

50 mL

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An advanced overnight repair cream with vegan, exosome-delivered EGF, an NAD+ boost and a four-ceramide barrier blend that visibly firms, smooths and deeply hydrates aging skin.

Product Info

Hydrinity CÉLTHERA Advanced Overnight Repair Cream – An advanced night cream that pairs vegan, exosome-delivered EGF with an NAD+ boost and a four-ceramide barrier blend to visibly firm, smooth and deeply hydrate aging skin while you sleep.

ExoEGF™ Technology delivers oligopeptide-1, a vegan EGF peptide, in biomimetic exosome-style vesicles with a sustained 24-hour release, with no human-derived exosomes or growth factors
A Centella secretome concentrate and a senolytic renewal complex support the skin's natural renewal processes
Sunflower sprout extract helps support the skin's own NAD+ for a more energized, resilient-looking complexion
Ceramides NP, NS, EOP and AP, cholesterol, hyaluronic acid and ectoin replenish the barrier and lock in moisture
In Hydrinity's clinical testing, the brand reports a 212% improvement in overall hydration, 100% visible improvement in overall skin appearance and 78% softer skin
Fragrance-free and designed to complement a nighttime retinol or retinal routine

Who benefits? Anyone noticing fine lines, lost firmness, dullness or dehydration who wants a night cream that does more than moisturize, including dry, mature and sensitive skin and anyone using a retinoid at night.

How to Use

Step 1: In the evening, cleanse the skin. Hydrinity recommends PRELUDE Facial Treatment Cleanser.
Step 2: Apply any mists and serums first.
Step 3: Dispense 1-2 pumps and smooth evenly over the face, neck and décolleté.
Step 4: Massage gently until fully absorbed.
Step 5: Use nightly as the last step of your evening routine, and wear a broad-spectrum sunscreen during the day.

Caution: For external use only. Avoid contact with eyes. If you also use a retinoid, introduce it gradually and adjust frequency to your skin's tolerance. Discontinue use if irritation occurs.

Ingredients

Key Ingredients: Behenic Acid, Caprylic Capric Triglyceride, Centella Asiatica Leaf Extract, Ceramide Ap, Ceramide Eop, Ceramide Np, Ceramide Ns, Cholesterol, Decyl Glucoside, Dipotassium Phosphate, Ectoin, Glycerin, Helianthus Annuus Sunflower Sprout Extract, Hyaluronic Acid, Hydroxyethyl Acrylate Sodium Acryloyldimethyl Taurate Copolymer, Lactic Acid, Maltodextrin, Malus Domestica Fruit Cell Culture Extract, Mannitol, Niacinamide, Oligopeptide 1, Phosphatidylcholine, Polyglyceryl 10 Stearate, Polyglyceryl 6 Behenate, Potassium Phosphate, Rhododendron Ferrugineum Extract, Sodium Cetearyl Sulfate, Sorbitan Isostearate, Terminalia Ferdinandiana Fruit Extract, Tetrasodium Glutamate Diacetate, Triethyl Citrate, Urea, Vitis Vinifera Grape Fruit Cell Extract

Full Ingredients: Water/Aqua/Eau, Caprylic/Capric Triglyceride, Glycerin, Squalane, Niacinamide, Urea, Maltodextrin, Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer, Glyceryl Stearate, PEG-100 Stearate, Cetearyl Alcohol, Oligopeptide-1, Hyaluronic Acid, Ectoin, Centella Asiatica Leaf Extract, Ceramide NP, Ceramide NS, Ceramide EOP, Ceramide AP, Cholesterol, Phosphatidylcholine, Malus Domestica Fruit Cell Culture Extract, Vitis Vinifera (Grape) Fruit Cell Extract, Rhododendron Ferrugineum Extract, Terminalia Ferdinandiana Fruit Extract, Helianthus Annuus (Sunflower) Sprout Extract, Lactic Acid, Mannitol, Dimethicone, Pentylene Glycol, Cetyl Alcohol, Behenic Acid, Triethyl Citrate, Polyglyceryl 10 Stearate, Polyglyceryl-6 Behenate, Sorbitan Isostearate, Decyl Glucoside, Sodium Cetearyl Sulfate, Xanthan Gum, Sodium Chloride, Sodium Citrate, Citric Acid, Sodium Hydroxide, Dipotassium Phosphate, Potassium Phosphate, Tetrasodium Glutamate Diacetate, Phenoxyethanol, Ethylhexylglycerin, Potassium Sorbate, Sodium Benzoate. Ingredient Lists Can Change. Please Refer To The Product Carton For The Most Current List.

Shipping

When will my order be shipped?

We aim to ship all products the same or next business day (Monday - Friday, excluding holidays) if in stock. If a delay occurs due to manufacturer backorders, we will notify you via email.

When will my order arrive?

Most orders are delivered within 2-3 business days, with over 99% arriving within 7 business days. Delivery times depend on the distance from our Atlanta, GA, location and the carrier.

How do I track my order?

Once your order ships, you will receive an email with a tracking number to monitor delivery progress.

What if my tracking number says "delivered" but I can't find my package?

Check your front/back porches, side doors, garage areas, and with neighbors. If the package is still missing after 2 business days, contact us for assistance.

SKU: 850046513343
Type: Moisturizers

Ideal for these Concerns: Dryness & Dehydration, Dullness, Fine Lines & Wrinkles, Loss of Firmness, Uneven Texture

Help Center?

Overnight Repair Cream

Renew, Firm & Hydrate Overnight

Suited for:

All skin types, especially dry, mature and sensitive skin

Target concerns:

Fine lines, loss of firmness, dullness, dryness

Benefits:

Firms, smooths, hydrates, strengthens

When to use:

Evenings, as the last step of your routine

The Night Cream, Upgraded

Why You'll Love It

A regenerative overnight cream that goes beyond hydration, pairing vegan EGF with NAD+ support and a complete ceramide barrier blend.

Vegan EGF, Timed Release

ExoEGF™ Technology releases oligopeptide-1 over 24 hours, timed to the skin's overnight repair cycle, to support firmer, smoother-looking skin.

NAD+ Boost

Sunflower sprout extract helps support the skin's own NAD+ production, which naturally declines with age, for skin that looks more energized.

Clinically Tested

In Hydrinity's clinical testing, the brand reports a 212% improvement in overall hydration and 78% softer skin.

Barrier Rebuilding

Ceramides NP, NS, EOP and AP with cholesterol replenish skin lipids and reduce age-related moisture loss.

Regenerative Night Actives

Key Ingredients

ExoEGF™ Technology

Vegan Growth Factor

Oligopeptide-1 is a lab-made peptide that mimics epidermal growth factor (EGF), one of the skin's own renewal signals. Hydrinity describes it as vegan and delivers it in stabilized, biomimetic exosome-style vesicles with a sustained 24-hour release, timed to the skin's overnight repair cycle, to support the look of collagen, elastin, firmness and smoothness. It is not derived from human cells or plasma.

Renewal Signals

Centella Secretome Concentrate

Hydrinity's Centella secretome concentrate is a blend of naturally derived signaling peptides from Centella asiatica that the brand says supports the skin's natural repair processes. The formula also contains apple and grape fruit cell extracts, rhododendron extract and Kakadu plum (Terminalia ferdinandiana) extract, alongside what Hydrinity calls a senolytic renewal complex, designed to target aging "zombie" cells.

NAD+ Boost

Sunflower Sprout Extract

NAD+ is a molecule the skin relies on for cellular energy and repair, and its levels decline with age. Hydrinity uses Helianthus annuus (sunflower) sprout extract to help support the skin's own NAD+ production for a more energized, resilient-looking complexion.

Need to Know

Frequently Asked Questions

Everything you need to know before choosing, using, and caring for your skin with Purity products.

Explore Help Center

How is CÉLTHERA different from a regular night cream?

Traditional night creams focus mainly on hydration. CÉLTHERA adds regenerative science on top of it: an exosome-delivered vegan EGF peptide, sunflower sprout extract to support the skin's own NAD+, a senolytic renewal complex, and a four-ceramide barrier blend with hyaluronic acid and ectoin. It is designed to address several visible signs of aging at once, not just dryness.

Are the exosomes and growth factors human-derived?

No. CÉLTHERA's ExoEGF™ Technology uses biomimetic vesicles, delivery carriers designed to mimic the tiny exosomes cells use to communicate, to deliver oligopeptide-1, a vegan peptide that mimics epidermal growth factor. Its Centella secretome comes from a plant. That makes it a different category from skincare built on human-derived exosomes or growth factors, such as platelet- or stem-cell-derived formulas.

Can I use it with my retinol or retinal?

Yes. Hydrinity designed CÉLTHERA to complement a nighttime retinoid routine, and in its clinical testing one group paired it with RetaXome Retinal Boost Treatment Pads every third night. Because retinoids can increase sensitivity, introduce them gradually and adjust how often you use them based on how your skin tolerates them.

Can I use it in the morning?

CÉLTHERA is formulated for evening use, with a 24-hour release timed to the skin's overnight repair cycle. In the morning, reach for a daytime moisturizer such as Hydrinity's HYDRI-C Daily Vitamin C Moisturizer and finish with a broad-spectrum sunscreen.

How soon will I see results?

Hydrinity reports noticeable improvements in as little as two weeks: in its clinical photos, visible improvement in overall appearance and hydration at three weeks with CÉLTHERA, and in firmness, smoothness and fine lines at two weeks when paired with RetaXome pads. Its study ran for 12 weeks of nightly use, so give it a full three months of consistent use to judge your results.

How long does a bottle last?

Used as directed, one to two pumps every night for the face, neck and décolleté, a 50 mL bottle lasts roughly two to four months, depending on how many pumps you use.